Clinical Trials

For Small Animals

Dentistry & Oral Surgery

The Contribution of Periodontal Treatment to the Management of Systemic Disease in Dogs and Cats

Who Qualifies:
Dogs and cats diagnosed with diabetes, renal failure, liver failure that did not receive any dental treatment in the year prior to joining the study.

More Information:
It has been demonstrated in humans that periodontal disease contributes to the development of atherosclerosis, premature birth and under-weight babies. It also was demonstrated that humans with diabetes tend to develop periodontal disease. In veterinary medicine there have been anecdotal reports suggesting that animals with diabetes and renal failure had their conditions better managed after having their periodontal disease treated.

To Enroll:
Call (970) 297-4304.

Dermatology

The Efficacy of Cetirizine on the Pruritus of Cats with Atopic Dermatitis

Who Qualifies:

More Information:
Antihistamines (like Cetirizine) are commonly used in allergic skin diseases of cats and dogs; so far no clinical studies have been performed evaluating their efficacy in cats with atopic dermatitis (environmental allergies). View our Client Information Sheet to learn more.

To Enroll:
Call (970) 297-4463.

Oncology

Animal Cancer Center

Who Qualifies:
Your pet may be eligible for one or more of our clinical trials, depending on the diagnosis and overall health of your animal. Your oncology veterinarian will discuss all standard treatment options with you. They will also offer you the opportunity to participate in clinical trials if appropriate, or to consult with the clinical trial coordinator to learn more.

More Information:
The oncology service runs many ongoing clinical trials for multiple different cancer types at any one time. Please view our available oncology clinical trials program to learn more about the studies that are currently enrolling patients.

To Enroll:
Call Kathy Paris, Consult Coordinator, at (970) 297-4195.

Ophthalmology

The Effects of Topical Naltrexone on Corneal Sensitivity and Tear Production in Diabetic Dogs

Who Qualifies:
All dogs must be confirmed diabetics based on previous history and blood work (documented glucosuria and blood glucose ≥200mg/dl) and have received insulin therapy for diabetes mellitus for at least two months prior to entering the study. Exclusion criteria include brachycephalic breed (pugs, bulldogs, boxers, etc.), significant systemic disease other than diabetes mellitus, pregnant or lactating, Schirmer tear test less than 5 mm wetting per minute, current treatment with topical ophthalmic medication, any current ocular disease requiring treatment.

More Information:
Our intent is to demonstrate the effectiveness of topically applied naltrexone in increasing the corneal sensitivity, tear production and tear film break up time in diabetic dogs. If this response can be documented, topical naltrexone could be used to improve the quality of vision and decrease suffering due to corneal disease in diabetic dogs.

To Enroll:
Email Dr. Trevor Arnold at tsarnold@colostate.edu.

For Equine

Equine Medicine & Surgery

Determining the Effectiveness of a New Anti-Inflammatory Agent on Clinical Characteristics of Horses with Severe Gastrointestinal Disease

Who Qualifies:
Adult horses (>1 year old) with surgical disease of the gastrointestinal tract or diarrhea.

More Information:
The purpose of this study is to characterize the efficacy of phenylmethimazole, a novel and potent anti-inflammatory agent, in reducing signs of endotoxemia and inflammation (high heart rate, pain, reddened mucous membranes, fever) in horses with severe colic or colitis (diarrhea).

Contact Information:
Call Dr. Diana Hassel at (970) 297-4271